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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
37.88
Human Site:
S176
Identified Species:
69.44
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
S176
S
A
K
L
S
D
K
S
R
Y
D
Y
F
A
R
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
I139
I
S
R
V
V
A
V
I
G
P
D
N
S
E
S
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
I139
V
P
R
V
V
A
V
I
G
P
D
N
S
D
A
Dog
Lupus familis
XP_541867
872
95696
S176
S
A
K
L
S
D
K
S
R
Y
D
Y
F
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
S176
S
A
K
L
S
D
K
S
R
Y
D
Y
F
A
R
Rat
Rattus norvegicus
P31421
872
95755
S176
S
A
K
L
S
D
K
S
R
Y
D
Y
F
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
S176
S
A
K
L
S
D
K
S
R
Y
D
Y
F
A
R
Chicken
Gallus gallus
XP_416842
879
98936
S182
S
A
K
L
S
D
K
S
R
Y
D
Y
F
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
S181
A
T
I
L
S
D
K
S
R
F
P
A
F
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
T189
A
K
T
L
S
D
K
T
R
F
D
L
F
A
R
Honey Bee
Apis mellifera
NP_001011624
933
103448
T200
A
K
A
L
S
D
K
T
R
F
D
Y
F
A
R
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
N233
N
A
D
L
S
D
K
N
R
F
E
Y
F
A
R
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
S750
S
A
R
L
S
D
K
S
R
F
E
F
F
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
100
100
N.A.
53.3
N.A.
60
66.6
66.6
73.3
P-Site Similarity:
100
26.6
20
100
N.A.
100
100
N.A.
100
100
N.A.
66.6
N.A.
80
86.6
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
62
8
0
0
16
0
0
0
0
0
8
0
77
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
85
0
0
0
0
77
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
39
0
8
85
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
0
16
47
0
0
0
85
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
85
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
16
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
16
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
24
0
0
0
0
0
85
0
0
0
0
0
85
% R
% Ser:
54
8
0
0
85
0
0
62
0
0
0
0
16
0
8
% S
% Thr:
0
8
8
0
0
0
0
16
0
0
0
0
0
0
0
% T
% Val:
8
0
0
16
16
0
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
47
0
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _